Primary service 02

IVRT & IVPT Support

Four modules covering study materials, wet-lab execution, skin sample processing, and optional analysis and reporting. Select a single module or connect the full path. Study design and interpretation are provided directly; laboratory work is available by project, with study site, methods and responsible parties confirmed during feasibility review.

Discuss an IVRT / IVPT project

01Study Materials
02Wet-Lab Work
03Sample Processing
04Analysis & Reporting

Any module can be selected on its own. Modules 2 and 3 are commonly combined; module 4 is optional.

Study Materials & Consumables

Research-use pig-ear skin, IVRT membranes, diffusion cell accessories and consumables—specification defined directly, sourcing coordinated per project.

Where this helps

You are planning IVRT or IVPT work but lack research-use skin, membranes, cell accessories or consumables.
You need specification, documentation and acceptance requirements defined before sourcing.
You are not sure whether your existing setup suits the endpoints you need.

What we provide

Provided directly

Specification definition for research-use skin, membranes and consumables
Diffusion cell, accessory and container selection guidance
Source documentation, acceptance criteria and handling requirements

Available by project

Sourcing coordination for research-use pig-ear skin
IVRT synthetic membrane and filter selection and supply coordination
Apparatus, accessory and consumable configuration

What you take away

Which materials your protocol actually requires
What documentation and acceptance conditions to insist on
Whether your existing setup is fit for the intended endpoints

Possible outputs

Material and consumable specification list · Accessory and consumables list or quotation · Source documentation and acceptance requirements · Delivery and handling plan

What to send first

Intended study type and endpoints · Existing equipment and consumables · Quantity and timing expectations · Destination country or region

Scope. Human skin is not provided. Pig-ear skin is for in vitro research only—not for human, transplant, clinical or medical use—and is not supplied as a sterile material by default. No inventory, fixed channel, in-house laboratory, equipment ownership or distribution authorisation is implied. Source, availability, cold chain and lead time are confirmed per project.

IVRT & IVPT Wet-Lab Work

Execution of the agreed IVRT or IVPT run, returning labelled baseline samples for your own analysis.

Where this helps

You have test samples and need the run completed, with baseline samples returned for in-house analysis.
You need documented dosing, sampling and receptor replacement records.
You want the run performed to a protocol you have already defined.

What we provide

Provided directly

Protocol review and endpoint confirmation before the run

Available by project

IVRT membrane mounting, equilibration, dosing and timed sampling
IVPT pig-ear skin mounting, integrity check, dosing, exposure and sampling
Receptor replacement, apparatus status, deviation and anomaly records
Collection and labelling of receptor fluid, endpoint membranes and skin

What you take away

Whether the run executed as designed
Where deviations occurred and what they affect
Whether the samples collected can support your intended endpoint

Possible outputs

Run, dosing, sampling and replacement records · Receptor fluid samples split by group, timepoint and replicate · Endpoint membranes or unextracted pig-ear skin as agreed · Sample list, storage conditions and handover record

What to send first

Test samples · Protocol or intended endpoints · Who will perform the analysis · Storage and shipping constraints

What the wet-lab run produces. The module covers execution and labelled sample delivery; cumulative release or permeation, flux, lag time and statistics are not included by default. Schematic only — cell geometry, apparatus and conditions are confirmed per project.

Scope. This module covers wet-lab execution and sample delivery only. Extraction, chemical quantification, cumulative release or permeation calculation, flux, lag time, statistics and interpretation are not included by default. Study site, personnel and responsible parties are confirmed per project.

Skin Sample Processing & Separation

Post-study skin processed into defined, traceable compartments for you or your designated laboratory to extract and analyse.

Where this helps

You have completed, or will complete, IVPT work and want the skin processed into separate compartments.
You need tape strips, epidermis and dermis separated and packaged to a defined scheme.
You want traceable sample handling without commissioning the analysis itself.

What we provide

Available by project

Surface wash, rinse or swab collection
Tape stripping, numbered individually or pooled as specified
Epidermis and dermis separation and separate packaging
Sectioning, numbering and packaging of whole or defined-area skin
Donor chamber, apparatus rinse or dosing tool recovery samples
Storage, cold chain and handover under confirmed conditions

What you take away

A defined, traceable set of skin compartments
What each sample can and cannot support analytically
Whether the compartment scheme matches your intended calculation

Possible outputs

Unanalysed surface wash, rinse or swab samples · Individual or pooled tape strips · Separately packaged epidermis, dermis or defined-area skin · Compartment map, sample list, storage conditions and handover record

What to send first

Post-study skin or samples, where the run was performed elsewhere · Required compartments and numbering scheme · Storage and shipping constraints · Your intended calculation

Where each delivered sample comes from. LumiMicro performs the separation and hands over labelled, unextracted compartments; retained amount, layer ratio, recovery and mass balance are calculated by whoever runs the analysis. Schematic only — not to scale, and not a depiction of any specific study.

Scope. LumiMicro performs the processing; extraction and quantification are carried out by you or your designated laboratory. Retained amount, layer ratio, total recovery, mass balance, statistics and interpretation are not included by default. Feasibility is reviewed separately where samples originate from a run performed elsewhere.

Analytical & Reporting Support

Optional. For projects without a suitable analytical route, or where results need structuring into a technical report. Skip this module if you have your own method or laboratory.

Where this helps

You have no suitable analytical route for the sample matrix and target range.
You have data and want it structured into a technical report.
You have a report or protocol from another party and want it reviewed.

What we provide

Provided directly

Analytical route discussion based on sample matrix and target concentration range
Review of data, protocols or reports produced by you or your laboratory
Structuring of calculations, figures, limitations and next steps, where data quality allows

Available by project

Sample extraction and quantification by HPLC, LC–MS/MS or another agreed method, confirmed separately

What you take away

Whether your analytical route fits the matrix and concentration range
Whether the data supports the conclusion being drawn
What the report can and cannot claim
What to add before the evidence is decision-grade

Possible outputs

Agreed analytical plan, results or data tables · Quality control and deviation summary · Structured technical report or report review note

What to send first

Sample matrix and target concentration range · Existing methods, data or reports · Who will perform the analysis · The decision the report needs to support

Scope. Analytical site, methods, suitability, validation status, quality system, raw data and report responsibility are confirmed per project. This module does not constitute GLP/GMP, clinical, registration or regulatory acceptance, and implies no certainty of outcome.

Common combinations

If you are unsure which module fits, describe what you already have and what you need to receive.

Your situation	Suggested combination	Main delivery
Running the study yourself, only missing materials	Module 1	Research-use skin, membranes, accessories and consumables with documentation
Need the wet-lab run completed, analysing in-house	Module 2	Receptor fluid, endpoint membranes or unextracted skin, plus run records
Need the run and separated skin compartments	Modules 2 + 3	Receptor fluid, tape strips, epidermis, dermis and other unanalysed samples
Need a full path from materials to report	Modules 1 + 2 + 3, module 4 as needed	An integrated delivery path confirmed per project
Have samples or data, need analysis or reporting	Module 4	Agreed results, structured technical report or review note

Not sure which to choose? Describe your current position and intended delivery, and we will define the smallest sufficient combination.

Start with a non-confidential question.

Tell us what you already have—samples, skin, membranes, equipment, an analytical method or an external laboratory—and what you need to receive. We help define the smallest sufficient combination.

Discuss an IVRT / IVPT project